Fractional CO2 achieves 26–50% periorbital wrinkle improvement and 40–75% acne scar improvement in clinical studies. Results are generally visible by weeks 3–4 and continue improving for months as collagen remodels.
In one 60-patient study of moderate-to-severe atrophic acne scars, 43.3% of patients achieved more than 50% improvement after fractional CO2 treatment, with rolling and superficial boxcar scars responding best. The final appearance settles between months three and six. In practice, most of our patients notice the inflection point around week four when the pinkness fades and the new skin texture becomes obvious.
Results typically last 3–5 years with consistent sunscreen use and sun protection; annual CoolPeel sessions help prolong and maintain them.
What CO2 cannot do
CO2 is exceptional for texture, tone, wrinkles, and scarring. It will not lift volume loss, it will not replace filler in hollow areas, and it will not fix dynamic wrinkles caused by muscle movement. For those goals, we plan combination treatments.
Clinical evidence, in plain English
A 2025 expert consensus in Lasers in Surgery and Medicine reviewed the current standard of care: Fitzpatrick I is optimal (100% expert agreement), Fitzpatrick II is acceptable (76%), and the ideal candidate age is 40–60 (82%). For atrophic acne scars, fractional CO2 produces a 40–75% improvement on the ECCA scale, measured at three and six months post-treatment. Long-term follow-up data from Weinstein's 2,123-patient series shows that the side effect profile is predictable and the improvements durable, with most patients maintaining their gains at 2+ years.
Clinical data is one piece of the decision. The other is an honest candidacy conversation — which is what a consultation with Dr. Borakowski is designed to give you.